英文論文

2019以前

原著論文

Takei Y, Takahashi S, Nakasatomi M, Sakairi T, Ikeuchi H, Kaneko Y, Hiromura K, Nojima Y, Maeshima A.
Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis.  
PLoS One. 2019 Oct 15;14(10):e0223703.

Mishima K, Nakasatomi M, Takahashi S, Ikeuchi H, Sakairi T, Kaneko Y, Hiromura K, Nojima Y, Maeshima A.
Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel.  
PLoS One. 2019 Oct 9;14(10):e0223496.

Shibusawa R, Yamada E, Okada S, Nakajima Y, Bastie CC, Maeshima A, Kaira K, Yamada M.
Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death.  
Sci Rep. 2019 Jul 8;9(1):9887.

Masuda T, Ohara K, Nagayama I, Matsuoka R, Murakami T, Nakagawa S, Oka K, Asakura M, Igarashi Y, Fukaya Y, Miyazawa Y, Maeshima A, Akimoto T, Saito O, Nagata D.
Impact of serum albumin levels on the body fluid response to tolvaptan in chronic kidney disease patients.  
Int Urol Nephrol. 2019 Sep;51(9):1623-1629.

Iriuchishima H, Maeshima A, Takahashi S, Ishizaki T, Yokohama A, Tsukamoto N, Saitoh T, Murakami H, Handa H.
Activin A: a novel urinary biomarker of renal impairment in multiple myeloma.  
Biosci Rep. 2019 May 31;39(5). pii: BSR20190206.

Nakasatomi M, Takahashi S, Sakairi T, Ikeuchi H, Kaneko Y, Hiromura K, Nojima Y, Maeshima A.
Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF.  
PLoS One. 2019 Mar 7;14(3):e0212991.

Nagayama I, Masuda T, Nakagawa S, Murakami T, Ohara K, Matsuoka R, Kobayashi T, Maeshima A, Akimoto T, Saito O, Muto S, Nagata D.
Different Effects on Fluid Distribution between Tolvaptan and Furosemide in a Liver Cirrhosis Patient with Chronic Kidney Disease.  
Intern Med. 2019 Jun 1;58(11):1587-1591.

Ohara K, Masuda T, Murakami T, Imai T, Yoshizawa H, Nakagawa S, Okada M, Miki A, Myoga A, Sugase T, Sekiguchi C, Miyazawa Y, Maeshima A, Akimoto T, Saito O, Muto S, Nagata D.
Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on fluid distribution: A comparison study with furosemide and tolvaptan.  
Nephrology (Carlton). 2019 Sep;24(9):904-911.

Ikeuchi H, Koinuma K, Nakasatomi M, Sakairi T, Kaneko Y, Maeshima A, Yamazaki Y, Okamoto H, Mimura T, Mochida S, Nojima Y, Hiromura K.
Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review.  
Case Rep Rheumatol. 2018 Jul 26;2018:6873276.

Tabei A, Watanabe M, Ikeuchi H, Nakasatomi M, Sakairi T, Kaneko Y, Maeshima A, Kaira K, Hirato J, Nojima Y, Hiromura K.
The Analysis of Renal Infiltrating Cells in Acute Tubulointerstitial Nephritis Induced by Anti-PD-1 Antibodies: A Case Report and Review of the Literature.  
Intern Med. 2018 Nov 1;57(21):3135-3139.

Hamatani H, Sakairi T, Ikeuchi H, Kaneko Y, Maeshima A, Nojima Y, Hiromura K.
TGF-β1 alters DNA methylation levels in promoter and enhancer regions of the WT1 gene in human podocytes.  
Nephrology (Carlton). 2019 May;24(5):575-584.

Mochizuki K, Kayakabe K, Hiromura K, Ando M, Sakurai N, Ikeuchi H, Sakairi T, Kaneko Y, Maeshima A, Nojima Y.
Successful treatment of severe crescentic lupus nephritis by multi-target therapy using tacrolimus and mycophenolate mofetil.  
CEN Case Rep. 2015 Nov;4(2):126-130.

Takahashi S, Nakasatomi M, Takei Y, Ikeuchi H, Sakairi T, Kaneko Y, Hiromura K, Nojima Y, MaeshimaA.
Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury.  
Sci Rep. 2018 Mar 26;8(1):5176.

Kadiombo AT, Maeshima A, Kayakabe K, Ikeuchi H, Sakairi T, Kaneko Y, Hiromura K, Nojima Y.
Involvement of Infiltrating Macrophage-derived Activin A in the Progression of Renal Damage in MRL-lpr Mice.
Am J Physiol Renal Physiol. 2017 Feb 1;312(2):F297-F304

Ikeuchi H, Hiromura K, Kayakabe K, Tshilela KA, Uchiyama K, Hamatani H, Sakairi T, Kaneko Y, Maeshima A, Nojima Y.
Renal outcomes in mixed proliferative and membranous lupus nephritis (Class III/IV + V): A long-term observational study.
Mod Rheumatol. 2016 Apr 26:1-6.

Sakairi T, Hiromura K, Kaneko Y, Maeshima A, Hirato J, Nojima Y.
Histological findings in the spleen affected by adult-onset Still's disease: a report of three cases.
Clin Exp Rheumatol. 2016 34(3):566-7.

Nakasatomi M, Maeshima A, Mishima K, Ikeuchi H, Sakairi T, Kaneko Y, Hiromura K, Nojima Y.
Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats.
Fibrogenesis Tissue Repair. 8: 12. 2015.

Bussolati B, Maeshima A, Peti-Peterdi J, Yokoo T, Lasagni L.
Renal Stem Cells, Tissue Regeneration, and Stem Cell Therapies for Renal Diseases.
Stem Cells Int. 2015: 302792.

Tshilela KA, Ikeuchi H, Matsumoto T, Kuroiwa T, Sakurai N, Sakairi T, Kaneko Y, Maeshima A, Hiromura K, Nojima Y.
Glomerular cytokine expression in murine lupus nephritis.
Clin Exp Nephrol. 2016 Feb;20(1):23-9

Kanasaki K, Maeshima A, Taduri G, Revuelta I
Combating kidney fibrosis.
Biomed Res Int. 2014;2014:679154. doi: 10.1155/2014/679154. Epub 2014 Sep 7.

Hamatani H, Hiromura K, Sakairi T, Takahashi S, Watanabe M, Maeshima A, Ohse T, Pippin JW, Shankland SJ, Nojima Y.  
Expression of a Novel Stress-inducible Protein, Sestrin 2, in Rat Glomerular Parietal Epithelial Cells.  
Am J Physiol Renal Physiol 2014 Sep 15;307(6):F708-17

Motohashi R, Ikeuchi H, Hiromura K, Ohishi Y, Sakurai N, Sakairi T, Kaneko Y, Maeshima A, Nojima Y.  
Two cases of ulcerative colitis developing in rheumatoid arthritis patients during abatacept therapy.  
Scand J Gastroenterol. 2014 Oct;49(10): 1270-1

Maeshima A, Mishima K, Yamashita S, Nakasatomi M, Miya M, Sakurai N, Sakairi T, Ikeuchi H, Hiromura K, Hasegawa Y, Kojima I, Nojima Y
Follistatin, an activin antagonist, ameliorates renal interstitial fibrosis in a rat model of unilateral ureteral obstruction.
Biomed Res Int. 2014: 376191.

Ikeuchi H, Hiromura K, Takahashi S, Mishima K, Sakurai N, Sakairi T, Kaneko Y, Maeshima A, Kuroiwa T, Nojima Y.
Efficacy and safety of multi-target therapy using a combination of tacrolimus, mycophenolate mofetil and a steroid in patients with active lupus nephritis.
Mod Rheumatol. 2014 Jul;24(4):618-25

Takahashi S, Tomioka M, Hiromura K, Sakairi T, Hamatani H, Watanabe M, Ikeuchi H, Kaneko Y, Maeshima A, Aoki T, Ohnishi H, Matozaki T, Nojima Y.
SIRPα signaling regulates podocyte structure and function.  
Am J Physiol Renal Physiol. 2013 Sep;305(6):F861-70.

Takahashi S, Hiromura K, Tsukida M, Ohishi Y, Hamatani H, Sakurai N, Sakairi T, Ikeuchi H, Kaneko Y, Maeshima A, Kuroiwa T, Yokoo H, Aoki T, Nagata M, Nojima Y.
Nephrotic Syndrome Caused by Immune-Mediated Acquired LCAT Deficiency.
J Am Soc Nephrol. 2013 Jul;24(8):1305-12

Mishima K, Maeshima A, Miya M, Sakurai N, Ikeuchi H, Hiromura K, Nojima Y.
Involvement of N-type Ca (2+) channels in the fibrotic process of the kidney in rats.
Am J Physiol Renal Physiol. 2013 Mar 15; 304(6): F665-73

Kayakabe K, Kuroiwa T, Sakurai N, Ikeuchi H, Kadiombo AT, Sakairi T, Kaneko Y, Maeshima A, Hiromura K, Nojima Y.
Interleukin-1β measurement in stimulated whole blood cultures is useful to predict response to anti-TNF therapies in rheumatoid arthritis.  
Rheumatology (Oxford). 2012 Sep;51(9):1639-43

Kayakabe K, Kuroiwa T, Sakurai N, Ikeuchi H, Kadiombo AT, Sakairi T, Matsumoto T, Maeshima A, Hiromura K, Nojima Y.
Interleukin-6 promotes destabilized angiogenesis by modulating angiopoietin expression in rheumatoid arthritis.  
Rheumatology (Oxford). 2012 Sep;51(9):1571-9

Miya M, Maeshima A, Mishima K, Sakurai N, Ikeuchi H, Kuroiwa T, Hiromura K, Nojima Y.
Age-related decline in label-retaining tubular cells: implication for reduced regenerative capacity after injury in the aging kidney.  
Am J Physiol Renal Physiol. 2012 Mar;302(6): F694-702.

Umemoto A, Ikeuchi H, Hiromura K, Hamatani H, Sakurai N, Sakairi T, Matsumoto T, Maeshima A, Kuroiwa T, Nojima Y.
Hydronephrosis caused by a relapse of granulomatosis with polyangiitis (Wegener’s).  
Mod Rheumatol. 2012 Aug;22(4):616-20

Miya M, Maeshima A, Mishima K, Sakurai N, Ikeuchi H, Kuroiwa T, Hiromura K, Yokoo H, Nojima Y.
Enhancement of In Vitro Human Tubulogenesis by Endothelial Cell-derived Factors: Implications for In Vivo Tubular Regeneration after Injury.
Am J Physiol Renal Physiol. 2011 Aug;301(2):F387-95.

Takahashi S, Hiromura K, Sakurai N, Matsumoto T, Ikeuchi H, Maeshima A, Kaneko Y, Kuroiwa T, Nojima Y.
Efficacy and safety of tacrolimus for induction therapy in patients with active lupus nephritis.
Mod Rheumatol. 2011 Jun;21(3):282-9

Sakairi T, Hiromura K, Takahashi S, Hamatani H, Takeuchi S, Tomioka M, Maeshima A, Kuroiwa T, Nojima Y.
Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivo.
Nephrology (Carlton). 2011 Jan;16(1):76-86.

Yoshida Y, Fukuda N, Maeshima A, Yamamoto C, Matsumoto T, Ueno T, Nojima Y, Matsumoto K, Soma M.
Treatment with valsartan stimulates endothelial progenitor cells and renal label-retaining cells in hypertensive rats.
J Hypertens. 2011 Jan;29(1):91-101.

Sakurai N, Kuroiwa T, Kayakabe K, Matsumoto T, Maeshima A, Hiromura K, Nojima Y.
Insulin-like growth factor binding protein-related protein 1 is expressed in rheumatoid synovium and regulates synovial fibroblast proliferation.
Mod Rheumatol. 2011 Feb;21(1):63-72.

Tomioka M, Hiromura K, Sakairi T, Takeuchi S, Maeshima A, Kaneko Y, Kuroiwa T, Takeuchi T, Nojima Y.
Nestin is a novel marker for renal tubulointerstitial injury in immunoglobulin A nephropathy.
Nephrology (Carlton). 2010 Aug;15(5):568-74.

Takeuchi S, Hiromura K, Tomioka M, Takahashi S, Sakairi T, Maeshima A, Kaneko Y, Kuroiwa T, Nojima Y.
The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis.
Nephron Exp Nephrol. 2010;116(1):e3-10.

Sakurai N, Kuroiwa T, Ikeuchi H, Hiramatsu N, Takeuchi S, Tomioka M, Shigehara T, Maeshima A, Kaneko Y, Hiromura K, Kopp JB, Nojima Y
Fluvastatin prevents podocyte injury in a murine model of HIV-associated nephropathy.
Nephrol Dial Transplant. 24(8):2378-83, 2009

Sakurai N, Kuroiwa T, Ikeuchi H, Hiramatsu N, Maeshima A, Kaneko Y, Hiromura K, Nojima Y
Expression of IL-19 and its receptors in RA: potential role for synovial hyperplasia formation.
Rheumatology (Oxford). 47(6):815-20, 2008

Hiramatsu N, Kuroiwa T, Ikeuchi H, Maeshima A, Kaneko Y, Hiromura K, Ueki K, Nojima Y
Revised classification of lupus nephritis is valuable in predicting renal outcome with an indication of the proportion of glomeruli affected by chronic lesions.
Rheumatology (Oxford) 47(5):702-7, 2008

Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK
Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct.  
J Am Soc Nephrol 18(12):3147-55, 2007

Ideura H, Hiromura K, Hiramatsu N, Shigehara T, Takeuchi S, Tomioka M, Sakairi T, Yamashita S, Maeshima A, Kaneko Y, Kuroiwa T, Kopp JB, Nojima Y
Angiotensin II provokes podocyte injury in murine model of HIV-associated nephropathy.  
Am J Physiol Renal Physiol 293(4):F1214-21, 2007

Sakairi T, Hiromura K, Yamashita S, Takeuchi S, Tomioka M, Ideura H, Maeshima A, Kaneko Y, Kuroiwa T, Nangaku M, Takeuchi T, Nojima Y
Nestin expression in the kidney with an obstructed ureter.  
Kidney Int 72(3):307-18, 2007

Maeshima A, Vaughn DA, Choi Y, Nigam SK
Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.  
Dev Biol 295(2): 473-85, 2006

Maeshima A, Sakurai H, Nigam SK
An adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into the developing Kidney.  
J Am Soc Nephrol 17(1): 188-98, 2006

Yamashita S, Maeshima A, Nojima Y
Involvement of renal progenitor tubular cells in epithelial-to-mesenchymal transition in fibrotic rat kidneys.  
J Am Soc Nephrol 16(7): 2044-51, 2005

Ikeuchi H, Kuroiwa T, Yamashita S, Hiramatsu N, Maeshima A, Kaneko Y, Hiromura K, Ueki K, Nojima Y
Fluvastatin reduces renal fibroblast proliferation and production of type III collagen: therapeutic implications for tubulointerstitial fibrosis.  
Nephron Exp Nephrol 97(4): e115-122, 2004

Maeshima K, Maeshima A, Hayashi Y, Kishi S, Kojima I
Crucial role of activin a in tubulogenesis of endothelial cells induced by vascular endothelial growth factor.  
Endocrinology 145(8): 3739-45, 2004

Wada W, Maeshima A, Zhang YQ, Hasegawa Y, Kuwano H, Kojima I
Assessment of the function of the betaC-subunit of activin in cultured hepatocytes.  
Am J Physiol Endocrinol Metab 287(2): E247-54, 2004

Yamashita S, Maeshima A, Kojima I, Nojima Y
Activin A is a potent activator of renal interstitial fibroblasts.  
J Am Soc Nephrol 15(1): 91-101, 2004

Maeshima A, Yamashita S, Nojima Y
Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney.  
J Am Soc Nephrol 14(12): 3138-3146, 2003

Ota F, Maeshima A, Yamashita S, Ikeuchi H, Kaneko Y, Kuroiwa T, Hiromura K, Ueki K, Kojima I, Nojima Y
Activin A induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.  
Arthritis Rheum 48(9): 2442-2449, 2003

Maeshima A, Yamashita S, Maeshima K, Kojima I, Nojima Y
Activin A produced by ureteric bud is a differentiation factor for metanephric mesenchyme.  
J Am Soc Nephrol 14(6): 1523-1534, 2003

Maeshima A, Maeshima K, Nojima Y, Kojima I
Involvement of Pax-2 in the action of activin A on tubular cell regeneration.  
J Am Soc Nephrol 13(12): 2850-2859, 2002

Zhang YQ, Zhang H, Maeshima A, Kurihara H, Miyagawa J, Takeuchi T, Kojima I
Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass.  
Endocrinology 143(9): 3540-3547, 2002

Maeshima A, Nojima Y, Kojima I
Activin A: an autocrine regulator of cell growth and differentiation in renal proximal tubular cells.  
Kidney Int 62(2): 446-454, 2002

Maeshima A, Zhang YQ, Nojima Y, Naruse T, Kojima I
Involvement of the activin-follistatin system in tubular regeneration after renal ischemia in rats.  
J Am Soc Nephrol 12(8): 1685-1695, 2001

Maeshima A, Zhang YQ, Furukawa M, Naruse T, Kojima I
Hepatocyte growth factor induces branching tubulogenesis in MDCK cells by modulating the activin-follistatin system.
Kidney Int 58(4): 1511-1522, 2000

Kogure K, Zhang YQ, Maeshima A, Suzuki K, Kuwano H, Kojima I
The role of activin and transforming growth factor-beta in the regulation of organ mass in the rat liver.
Hepatology 31(4): 916-921, 2000

Maeshima A, Shiozaki S, Tajima T, Nakazato Y, Naruse T, Kojima I
Number of glomeruli is increased in the kidney of transgenic mice expressing the truncated type II activin receptor.  
Biochem Biophys Res Commun 268(2): 445-449, 2000

Maeshima A, Murakami H, Sadakata H, Saitoh T, Matsushima T, Tamura J, Karasawa M, Naruse T
Eosinophilic gastroenteritis presenting with acute pancreatitis.  
J Med 28(3-4): 265-272, 1997

著書

前嶋明人
「レジデントのための腎臓教室」ベストティーチャーに教わる全14章 日本医事新報社
2017年11月 初版 2023年7月 第2版 

前嶋明人
かかりつけ医のための腎臓病診療ブラッシュアップ
2023年3月 金芳堂

Akito Maeshima
Daughter Cells: Properties, Characteristics and Stem Cells.
「Regeneration of the Kidney: Involvement of Intra-and Extra-Renal Stem Cells」 (pp.197-220) Novapublishers 2010


英文総説

Maeshima A, Takahashi S, Nakasatomi M, Nojima Y
Diverse Cell Populations Involved in Regeneration of Renal Tubular Epithelium Following Acute Kidney Injury.  
Stem Cells Int. 2015: 964849. Review.

Maeshima A, Nakasatomi M, Nojima Y
Regenerative Medicine for the Kidney. Renotropic factors, renal stem/progenitor cells, and stem cell therapy.
Biomed Res Int. 2014: 595493. Review.

Maeshima A
Label-retaining cells in the kidney. Origin of regenerating cells after renal ischemia.  
Clin Exp Nephrol 11(4): 269-74, 2007

Maeshima A, Miya M, Mishima K, Yamashita S, Kojima I, Nojima Y
Activin A: Autocrine Regulator of Kidney Development and Repair.  
Endocr J 55(1):1-9, 2008

Maeshima A, Nojima Y, Kojima I
The role of the activin-follistatin system in the developmental and regeneration processes of the kidney.  
Cytokine Growth Factor Rev 12(4): 289-298, 2002

Kojima I, Maeshima A, Zhang YQ
Role of the activin-follistatin system in the morphogenesis and regeneration of the renal tubules.  
Mol Cell Endocrinol 180(1-2): 179-182, 2001



和文総説

前嶋明人
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内科 118巻1号 Page111-120

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前嶋明人
「腎再生医療の実現を目指して」
The KITAKANTO MEDICAL JOURNAL 65:153-154, 2015

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日本医事新報 No.4699 2014日本医事新報社

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Medical Practice 31巻8号 Page1354-1356 2014文光堂

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Medical Practice 30巻6号1098, 2013 文光堂

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血液疾患と腎障害 
内科学(第10版) 1475-1476, 2013 朝倉書店

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溶血性尿毒症症候群 
内科学(第10版) 1476-1477, 2013 朝倉書店

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早期診断と治療「全身性エリテマトーデス」
内科 112巻1号33-37, 2013 南江堂

前嶋明人
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腎臓症候群(第2版) 405−408, 2012 日本臨床社

前嶋明人、野島美久
アミロイド腎 
腎・透析診療最新ガイドライン 総合医学社

前嶋明人、野島美久
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リウマチ科 47巻5号 Page481-487, 2012 科学評論社

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日本腎臓学会誌 50巻2号Page114-121

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医学のあゆみ Vol.199 No.13 1107-1112, 2001

小島至・前嶋明人
(総説)アクチビンシグナリングと腎臓の形態形成・再生 
蛋白質核酸酵素 vol.46 No.2  130-137, 2001

前嶋明人、野島美久、小島至
 【再生医学のフロンティア】 腎臓の再生医学 
Molecular Medicine Vol.38 No.1 68-76, 2001

和田渉、前嶋明人、小島至
(総説)フォリスタチンと再生医学  
最新医学 vol.55  別冊  205-215, 2000

前嶋明人、小島至
(総説)「図解ホルモンのすべて」アクチビン・インヒビン  
ホルモンと臨床 98‘春季増刊号p486-496

前嶋明人、小島至
(総説)体液性因子における骨・血管相互作用 -骨・血管とFGF-
Clinical Calcium vol.7 No.9 p32-37, 1997

前嶋明人、小島至
「ノックアウトマウス・データブック」 Follistatin  
Molecular Medicine Vol.34  臨時増刊号  p178-179, 1997